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One of the more unusual studies into ageing that has been published this month, has demonstrated that men experience a greater reduction in brain volume across more regions as they age than women do. The longitudinal study released in the Proceedings of the National Academy of Sciences examined 12,500 magnetic resonance imaging (MRI) scans taken from 4,726 people (with at least 2 scans per person taken on an average of 3 years apart). The study participants did not have Alzheimer's disease or any cognitive impairments and were control participants in 14 larger data sets.
The researchers compared the brain structures of individuals over time such as the thickness of grey matter and the size of the hippocampus (which is essential to memory). The results found a greater reduction in volume across more regions in the brains of men than for women. As one example, the postcentral cortex region (responsible for processing sensations of touch, pain, temperature and the body's own movements and position) declined by 2.0% per year in men and only 1.2% in women over the same period.
The results of the study, not surprisingly, led researchers to conclude that men age faster than women and have a shorter life expectancy. This is hardly new information. A question that remains unanswered by this study is why women are twice as likely to be diagnosed with Alzheimer's disease than men given their brains age more slowly.
For men, this study only assists with the impression that as they age, they become old codgers.
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